pentobarbital will reduce the extent or effect of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Loss of, or decreased response to tofacitinib may arise when coadministered with powerful CYP3A4 inducersWatch Closely (one)pentobarbital will lower the extent or effect of glecaprevir/pibrentasvir by im